Calendar

<<  November 2017  >>
MoTuWeThFrSaSu
303112345
6789101112
13141516171819
20212223242526
27282930123
45678910

View posts in large calendar

Another Powerful Painkiller Found in Prince's System: U-47700

From Eyewitness News 5 (Minneapolis/St. Paul):

Although it was a fentanyl overdose that killed Prince April 21, the medical examiner said it was part of a deadly chemical cocktail.

A source close to the investigation says U47700 was part of the mixture.  The potent painkiller is a synthetic opioid, eight times stronger than morphine.

Investigative sources told reporter Beth McDonough that Prince may have thought he was taking a legitimate painkiller, like hydrocodone or fentanyl, that unknowingly also had U-47700 in it.

The pills often look just like other medications.  Plus, U47700 can be resistent to the life-saving antidote Narcan. 

Because U-47700 is not considered a controlled substance by state or federal agents, it's not regulated.  The Drug Enforcement Administrations says it tends to be produced overseas in China or Eastern Europe.  It's widely available, easily accessible and affordable, about $40 online. 

A deadlier drug: Doctors suspect W-18 is spiking overdoses

From The Philadelphia Inquirer:

Legal synthetics have caused "upwards of 50 deaths" nationwide during the last four months, according to Barry Logan, director of the Center of Forensic Science and Education. The center is the nonprofit research arm of NMS Labs, which tests for the substances at its Willow Grove headquarters.

NMS confirmed one death in Illinois caused by W-18 and is investigating its role in another.

"The bigger problem right now is the designer opioid U-47700 and the designer fentanyl, furanyl, fentanyl," Logan said, adding that NMS had detected the two substances in a string of fatal overdoses that reached from Florida to Maine.


Expert offers warning signs for parents to tell if children are on drugs

From WFTV (Orange County, FL):

Dr. Barry Logan and his team attended the Ultra Music Festival in Miami in March, not for the music, but to collect saliva, urine and blood samples from concertgoers for federal drug research.

“It's a great venue for us to study some of what's going on in the designer drug market,” Dr. Barry Logan said.

The goal of Logan and his team is to identify new drugs and to help emergency room doctors stop overdoses before they become deadly.
 

Police warn against deadly new street drug W-18

From Radio Canada International:

W-18 is a synthetic opioid considered to be 10,000 times more powerful than morphine and 100 time stronger than fentanyl—a street drug which caused about 270 overdose deaths last year in the province of Alberta alone.

Four kilograms of a white powder seized by police in the Edmonton area in December 2015 was analysed and turns out to be W-18, a drug that is not yet a controlled substance in Canada.

The quantity is enough to produce millions of tablets, say police. Minute amounts can be deadly. Police are concerned that illicit labs creating tablets may not cut the drug properly and that overdoses will result.

Hospitals have been warned to be on the lookout for drug overdoses and deaths that might be linked to W-18. Dr. Laura Calhoun of the government of Alberta health service joined with police to warn the public: “Our message to the public is this: no matter what drug you use, fentanyl or W-18 may be hiding in it, and they may kill you.”

New synthetic drug shows up on streets of Northeast Ohio

From newsnet5 (Cleveland):

There is new drug is on the streets of Northeast Ohio and it can be deadly.

In fact, an overdose death in Lake County is believed to be the first in the state, said Doug Rohde, supervisor of Chemistry and Toxicology at the Lake County Crime Laboratory.

After an alert from Lorain County about a new drug and some more research Rohde discovered it was U-47700. It is a new opioid that is eight times more potent than morphine. It is also deadly. U-47700 is to blame for the deaths of 20 people in 9 states.

The synthetic opioid is so new that it has not yet been labeled illegal. But, Rohde said just because it is still legal does not mean that it is safe.

Synthetic opiate makers stay step ahead of US drug laws as overdose cases rise

From The Guardian:

W-18 is one of thousands of synthetic opiates that is not scheduled as a controlled substance and thus not subject to criminal drug penalties, and one of a handful of drugs that law enforcement officials and scientists say they have seen in increasing numbers in the last six months, as use, abuse and overdose deaths continues to rise.

Another, U-47700, which is seven to eight times stronger than morphine, has been the source of overdoses over the past year in at least 10 states since the first US incident was discovered in Knoxville, Tennessee, in June 2015.

Barry Logan, the executive director for the Center of Forensic Science and Education, said his lab has been able to track down 17 overdose cases of U-47700. And several other overdose deaths and hospitalizations have been identified by local law enforcement in Florida and northern Texas.

The uptick in overdoses and drug seizures involving opiates like W-18 and U-47700 follows actions taken by the Chinese government to criminalize more than 100 chemicals on 1 October 2015, according to Bare.

Once more traditional synthetic drugs were outlawed, chemists looked to more novel substances instead.

The banned chemicals included the makings of acetyl fentanyl, an illicit version or analogue of the powerful prescription painkiller fentanyl that is drastically exacerbating the opioid epidemic in the US. Flakka, a cathinone similar to bath salts, was also banned.

Logan said chemists are finding the recipes for these drugs from research books from the 1970s, when scientists were trying to invent alternatives to morphine.

“In order to find one drug like that you have to test hundreds of them,” said Logan. The result is that there are thousands of variations of research opiates, most of which were never meant to be tried on humans.
 

New Webinar- “Flakka”: The Truth Behind the Latest Designer Drug Media Storm

From: NMS Labs

Donna Papsun, a forensic toxicologist at NMS Labs, will be hosting a free webinar on Flakka, the new dangerous designer drug that is taking the country by storm.  "Flakka” is the latest street name referring to alpha-pyrrolidinophenone (alpha PVP), a novel psychoactive substance that has been on the recreational drug market since 2012.  Former street names include “Gravel”, which was allegedly alpha PVP mixed with lorazepam, and “Bath Salts”, a catch-all term referring to a number of synthetic stimulants.  This webinar will focus on the toxicology of alpha PVP and highlight the prevalence of this drug by recreational users.  Although the abuse of alpha PVP is not new, it is certainly a designer drug trend that deserves the attention of public health authorities, law enforcement, medical examiners, and toxicology laboratories. 

Register today and learn more about Flakka, Alpha PVP, and other novel psychoative substances as well as how they are effecting the world of toxicology.  The webinar will be held Monday, June 1st at 1pm and will last roughly a half hour.  You can register for the free webinar here

 

Researchers document drug use among Ultra Music Festival attendees

From: Miami Herald

Fair or not, after 16 years Ultra Music Festival has developed a reputation not only as a cornucopia of lights and sounds, but also as a smorgasbord of psychotropic uppers and downers.  But according to a federally funded study, if you ask 100 audience members to pee in a cup in exchange for a $20 Dunkin’ Donuts gift card, 80 just might test positive for drugs.

At least, researchers from the Center for Forensic Science Research & Education said that was their experience last year when they set up camp outside Bayfront Park and sought to document drug use among the thousands of ticket holders who flock to downtown Miami each year for three days of electronic dance music. The event typically sells more than 160,000 tickets.

Out of 145 voluntary participants, 72 percent admitted to having consumed marijuana, cocaine, molly or ecstasy during the past week. And for the 100-plus brave souls who went a step further and agreed to have their blood taken, or give a urine sample, researchers said they found that 58 percent and 80 percent, respectively, had recently consumed designer drugs.

The goal of the study, according to a summary of the results, was not to find out how many at Ultra are on drugs, but to get a better grasp of “some of the newly emerging and potentially dangerous new drugs popular in the [electronic dance music] community.”

“We found the participants at the event were very open with us about their knowledge of the drug scene and drug use,” said Barry Logan, the Pennsylvania-based center’s executive director. “We found a lot of the time what they thought they were taking was not what they were taking.”

Of the 104 urine samples, more than 80 percent tested positive for a synthetic drug, most commonly molly, followed by Alpha-PVP, a synthetic bath salt known as gravel, which ultimately killed 21-year-old Adonis Peña Escoto last year.

However, Logan said the survey was conducted with far too small a sample size — less than one tenth of a percent of the tickets sold for the festival — to be taken as any kind of statistical representation of the drug use at Ultra.

“A lot of people who read this assume it’s an indicator of prevalence, which I don’t think it is,” said Logan.

Now in its 16th year, Ultra is returning to downtown Miami in late March as an 18-and-older festival.


Read more here: http://www.miamiherald.com/news/local/community/miami-dade/article9709724.html#storylink=cpy

Designer drugs put youths at risk, but recipe changes tie officers’ hands

Via Dallas News

 A week before he died, the 15-year-old honors student had taken an illustrated book to pastures near his Frisco home looking for psychedelic mushrooms. He didn’t find any, so he tried what he thought was LSD on Dec. 14. Convulsions began within an hour after he ingested 25I, a synthetic hallucinogen more potent than LSD. The Collin County medical examiner ruled that his death was connected to the drug. In what appears to be a growing problem, three more overdoses possibly linked to 25I were reported in McKinney last weekend. They appear not to have been fatal.

Efforts to criminalize emerging designer drugs in Texas fell flat in the most recent legislative session, making it more challenging for law enforcement agencies to crack down on the problem.

Nationally, at least 19 deaths have been linked to a set of synthetic drugs known as the NBOMe compounds, including 25I, according to the Drug Enforcement Administration. The users ranged from 15 to 29 years old. Texas Poison Control Network has tallied 25 calls related to NBOMe since 2012. Six came from the Dallas-Fort Worth area.

Stymied in Austin

In November, the DEA temporarily added three NBOMe drugs to Schedule I.  In February, the Department of State Health Services added three NBOMe compounds to the state’s list of controlled substances. The temporary move allows prosecutors to pursue criminal charges, but only misdemeanors, regardless of the amount of the drugs.

Though the state banned K2 in 2011, other kinds of “fake pot” have surfaced since. And if the chemistry is slightly different from what’s in the law, dealers can avoid prosecution.

Law enforcement and public health officials said Huffman’s bills would address that problem by outlawing certain designer drugs and other compounds with the same core chemical structure.

Dueling experts

Like the federal government, Texas has provisions to cover analogs — drugs that are substantially similar to some illegal substances based on their chemical makeup or effects on users.

For every case, prosecutors would have to prove in court that the compound in question was similar enough to an illegal narcotic.

“It comes down to a battle of the expert witnesses,” said Samms, who wrote to lawmakers in support of Huffman’s proposed legislation.

And some cases don’t even make it to court if law enforcement or health officials can’t trace a drug.

NMS Labs in Pennsylvania, which does forensic testing for medical and legal clients across the country, handled its first NBOMe case in 2012.

“They’re very potent, so it takes very little drug to have its effects,” toxicologist Donna Papsun said. “The challenge was creating a test with a low enough detection level so we could properly detect it in the fluids.”

Posted: 4/22/2014 10:42:00 AM

Tags: , , , , , , , , ,

New synthetic drug investigated in Fishers teen’s death

From: Fox59

HAMILTON COUNTY, Ind. - Police have opened a criminal investigation into the death of a Hamilton County teen who made have died after ingesting synthetic drugs.

John Joseph Romaine, 18, was found unresponsive in his Fishers home Friday evening. According to his obituary, the Hamilton Southeastern High School senior died of cardiac arrest. The Hamilton County coroner is waiting on toxicology results before ruling an official cause, but police are looking into a possible overdose of synthetic drugs.

Police told FOX59 they found illegal drugs inside the home along with three men, including Romaine, who was unconscious.

Officers got there and observed a male lying on the floor and immediately began CPR until medics arrived," said Officer James Alvis, a spokesman for Fisher Police. All three were hospitalized, and Romaine was later pronounced dead.

A Reddit post, which appears to be written by Romaine's older brother, describes the night in detail and points the blame on a new synthetic drug called N-Bomb or NBOME. The author warns people not to use the drug and expressed deep regret over his brother's death.

FOX59 went to St. Vincent Carmel Hospital to find out more about the drug. Emergency room physician Dr. Marcus Hendry explained that it's a psychedelic drug that is often compared to LSD, but it is considered more powerful depending on the purity and dosage.

"They might experience agitation, hallucination, might get high fever, muscle injury, kidney failure, all the way to persistent seizures that may require the induction of a medical coma or even death as a result of persistent seizures or perhaps more commonly death." explained Hendry.

Police are now looking into the Reddit post and warning parents and teens to consider how dangerous synthetic drugs can be. They have not ruled out any arrests in this case.

Posted: 4/10/2014 2:18:00 PM

Tags: , , , , , , ,